Publikationen

2016

Fernandez-Palomo C, Schültke E, Bräuer-Krisch E, Laissue JA, Blattmann H, Seymour C, Mothersill C. Investigation of Abscopal and Bystander Effects in Immunocompromised Mice After Exposure to Pencilbeam and Microbeam Synchrotron Radiation. Health Phys.; 111(2):149-59. (2016). PMID:27356059

 

2015

Baumgart T, Kriesen S, Neels O, Hildebrandt G, Manda K. Investigation of epothilone B-induced cell death mechanisms in human epithelial cancer cells – in consideration of combined treatment with ionising radiation. Cancer Invest. 33(6):213-224 (2015). PMID: 25919223

Mathias D, Mitchel RE, Barclay M, Wyatt H, Bugden M, Priest ND, Whitman SC, Scholz M, Hildebrandt G, Kamprad M, Glasow A. Low-dose irradiation affects expression of inflammatory markers in the heart of ApoE-/- mice. PLoS One. (2015) in print; doi: 10.1371/journal.pone.0119661. PMID:25799423

Patties I, Haagen J, Dörr W, Hildebrandt G, Glasow A. Late inflammatory and thrombotic changes in irradiated hearts of C57BL/6 wild-type and atherosclerosis-prone ApoE-deficient mice. Strahlenther Onkol 191(2):172-179 (2015). PMID:25200359

Fernandez-Palomo C, Mothersill C, Bräuer-Krisch E, Laissue J, Seymour C, Schültke E. γ-H2AX as a marker for dose deposition in the brain of wistar rats after synchrotron microbeam radiation. PLoS One. 23; 10(3) (2015). PMID:25799425

 

2014

Haustein M, Ramer R, Linnebacher M, Manda K, Hinz B. Cannabinoids increase lung cancer cell lysis by lymphokine-activated killer cells via upregulation of ICAM-1. Biochem Pharmacol 92(2):312-325 (2014). PMID:25069049

Ramer R, Fischer S, Haustein M, Manda K, Hinz B. Cannabinoids inhibit angiogenic capacities of endothelial cells via release of tissue inhibitor of matrix metalloproteinases-1 from lung cancer cells. Biochem Pharmacol. 91:202-216 (2014). PMID:24976505

Manda K, Kavanagh JN, Buttler D, Prise KM, Hildebrandt G. Low dose effects of ionizing radiation on normal tissue stem cells. Mutat Res-Rev Mutat. 761:6-14 (2014). PMID:24566131

Acheva A, Aerts A, Rombouts C, Baatout S, Salomaa S, Manda K, Hildebrandt G, Kämäräinen M. Human 3-D tissue models in radiation biology: current status and future perspective. Int J Radiat Res. 12(2):81-98 (2014).

Patties I, Habelt B, Rosin B, Dörr W, Hildebrandt G, Glasow A. Late effects of local irradiation on the expression of inflammatory markers in the Arteria saphena of C57BL/6 wild-type and ApoE-knockout mice. Radiat Environ Biophys. 53(1):117-24 (2014). PMID:24071970

 

2013

Jaeger A, Baake J, Weiss DG, Kriehuber R. Glycogen synthase kinase-3beta regulates differentiation-induced apoptosis of human neural progenitor cells. Int J Dev Neurosci. 31(1):61-8 (2013). PMID:23085082 

Mitchel RE, Hasu M, Bugden M, Wyatt H, Hildebrandt G, Chen YX, Priest ND, Whitman SC. Low-dose radiation exposure and protection against atherosclerosis in ApoE(-/-) mice: the influence of p53 heterozygosity. Radiat Res. 179(2):190-9 (2013). PMID:23289388

Kadhim M, Salomaa S, Wright E, Hildebrandt G, Belyakov OV, Prise KM, Little MP. Non-targeted effects of ionising radiation-Implications for low dose risk. Mutat Res. 752(2):84-98 (2013). PMID:23262375

Buttler D, Mai JK, Ashwell KW, Andressen C. Clonogenic CD15 immunoreactive radial glial cells from the developing human lateral ganglionic eminence. Curr Pharm Biotechnol. 14(1):29-35 (2013). PMID: 23092258

 

2012

Rödel F#, Frey B#, Manda K, Hildebrandt G, Hehlgans S, Keilholz L, Seegenschmiedt MH, Gaipl US and Rödel C. Immunomodulatory properties and molecular effects in inflammatory diseases of low-dose X-irradiation. Frontiers in Molecular and Cellular Oncology (2012); DOI: 10.3389/fonc.2012.00120. (# both authors have contributed equally to this work). PMID:23057008

Manda K#, Glasow A#, Paape D, Hildebrandt G. Effects of ionizing radiation on the immune system with special emphasis on the interaction of dendritic cells and T cells. Frontiers in Molecular and Cellular Oncology. (2012); DOI: 10.3389/fonc.2012.00102. (# both authors have contributed equally to this work). PMID:22937525

Baumgart T, Kriesen S, Hildebrandt G, Manda K. Effect of epothilone B on cell cycle, metabolic activity, and apoptosis induction on human epithelial cancer cells - under special attention of combined treatment with ionizing radiation. Cancer Invest. 30(8):593-603 (2012). PMID:22909073

Rödel F, Frey B, Gaipl U, Keilholz L, Fournier C, Manda K, Schöllnberger H, Hildebrandt G,  Rödel C. Modulation of Inflammatory Immune Reactions by Low-Dose Ionizing Radiation: Molecular Mechanisms and Clinical Application. Curr Med Chem. 19:1741-1750 (2012). PMID:22414082

Baumgart T, Klautke G, Kriesen S, Kuznetsov S, Weiss DG, Fietkau R, Hildebrandt G, Manda K. Radiosensitizing effect of epothilone B on human epithelial cancer cells. Strahlenther Onkol. 188(2):177-184 (2012). PMID:22234539

Tiemann N, Hildebrandt G, Manda K. Unexpected effect of the monoclonal antibody Panitumumab on human cancer cells with different KRAS status. Med Oncol. 29(3):2276-2283 (2012). PMID:21842425

 

2011

Jahns J, Anderegg U, Saalbach A, Rosin B, Patties I, Glasow A, Kamprad M, Scholz M, Hildebrandt G. Influence of low dose irradiation on differentiation, maturation and T-cell activation of human dendritic cells. Mutat Res. 709-710:32-39 (2011). PMID:21376737

Mitchel, REJ, Hasu M, Bugden M, Wyatt H, Little M, Hildebrandt G, Priest ND, Whitman SC. Low Dose Radiation Exposure and Atherosclerosis in ApoE-/- Mice. Radiat Res. 175(5):665-676 (2011). PMID:21375359

Manda K, Kriesen S, Hildebrandt G, Fietkau R, Klautke G. Omega-3 fatty acid supplementation in cancer therapy: does Eicosapentaenoic acid influence the radiosensitivity of tumor cells? Strahlenther Onkol. 187(2):127-134 (2011). PMID:21267532

 

2010

Bogdándi EN, Balogh A, Felgyinszky N, Szatmári T, Persa E, Hildebrandt G, Sáfrány G, Lumniczky K. Low dose radiation effects on the immune system of mice after total body irradiation. Radiat Res. 174(4):480-489 (2010). PMID:20726712

Rödel F, Frey B, Capalbo G, Gaipl U, Keilholz L, Voll R, Hildebrandt G, Rödel C. Discontinuous induction of X-linked inhibitor of apoptosis in EA.hy.926 endothelial cells is linked to NF-kappaB activation and mediates the anti-inflammatory properties of low-dose ionising-radiation. Radiother Oncol. 97:346-351 (2010). PMID:20170972

Hildebrandt G. Non-cancer diseases and non-targeted effects. Mutat Res. 687(1-2):73-77 (2010). PMID:20097211

Jacquet P, Buset J, Neefs M, Vankerkom J, Benotmane MA, Derradji H,  Hildebrandt G, Baatout S. Transgenerational developmental effects and genomic instability after X-irradiation of preimplantation embryos: studies on two mouse strains. Mutat Res. 687(1-2):54-62 (2010). PMID:20096709

Salomaa S, Wright E,  Hildebrandt G, Kadhim M, Little M, Prise K, Belyakov OV.: Editorial to Mutation research special issue. Mutat Res. 687(1-2):1-2 (2010). PMID:20100499

Little, MP, Tawn, EJ, Tzoulaki, I, Wakeford, R, Hildebrandt, G, Paris, F, Tapio, S, Elliott, P: Review and meta-analysis of epidemiological associations between low and moderate doses of ionizing radiation and late circulatory disease risks, and their possible mechanisms. Radiat Environ Biophys. 49(2):139-153 (2010). PMID: 19862545

 

2009

Little MP, Tawn EJ, Tzoulaki I, Wakeford R, Hildebrandt G, Tapio S: Comments: The non-cancer mortality experience of male workers at British Nuclear Fuels plc, 1946–2005. Int J Epidemiol. 38(4):1159-1164 (2009). PM:18614611

Patties I, Jahns J, Hildebrandt G, Kortmann RD, Glasow A: Additive effects of 5’Aza-2’deoxycytidine and irradiation on clonogenic survival of human medullo-blastoma cell lines. Strahlenther Onkol. 185(5):331-338 (2009). PM:19440673

Fricke, S, Ackermann, M, Stolzing, A, Hilger, N, Schimmelpfennig, C, Jahns, J, Hildebrandt, G, Emmrich, F, Boltze, J, Kamprad, M, Sack, U: Allogeneic nonadherent stem cells facilitate hematopoietic recovery but do not lead to allogeneic engraftment. PLoS One. 4(7):e6157 (2009). PM:19582154

 

2008 und früher

Little MP, Tawn EJ, Tzoulaki I, Wakeford R, Hildebrandt G, Paris F, Tapio S, Elliott P: A systematic review of epidemiological associations between low and moderate doses of ionizing radiation and late cardiovascular effects, and their possible mechanisms. Radiat Res. 169:99-109 (2008). PM:18159955

Glasow A, Barrett A, Petrie K, Gupta R, Boix-Chornet M, Zhou DC, Grimwade D, Gallagher R, von Lindern M, Waxmann S, Enver T, Hildebrandt G, Zelent A: DNA methylation-independent loss of RARA gene expression in acute myeloid leukemia. Blood 111(4):2374-2377 (2008). PM:17993618

Rödel F, Keilholz L, Herrmann M, Sauer R, Hildebrandt G: Radiobiological mechanisms in inflammatory diseases of low dose radiation therapy. Int J Radiat Biol 83(6):357-366 (2007). PM:17487675

Leo C, Horn LC, Rauscher C, Hentschel B, Liebmann A, Hildebrandt G. Höckel M: Expression of erythropoietin and erythropoietin receptor in cervical cancer and relationship to survival, hypoxia, and apoptosis. Clin Cancer Res. 12(23):6894-6900 (2006). PM:17145806

Rödel F, Franz S, Sheriff A, Gaipl U, Heyder P, Hildebrandt G, Voll RE, Herrmann M: The CFSE distribution assay is a powerful technique for the analysis of radiation induced cell death and survival on a single cell level. Strahlenther Onkol. 181(7):456-462 (2005). PM:15995839

Schaue D, Jahns J, Hildebrandt G, Trott KR: Radiation treatment of acute inflam-mation in mice. Int J Radiat Biol. 81:657-667 (2005). PM:16368644

Rödel F, Hantschel M, Hildebrandt G, Schultze-Mosgau S, Rödel C, Herrmann M, Sauer R, Voll RE: Dose dependent biphasic induction and transcriptional activity of nuclear factor kappa B (NF-kB) in EA.hy.926 endothelial cells after low‑dose X-irradiation. Int J Radiat Biol. 80:115-123 (2004). PM:15164793

Liebmann A, Hindemith M, Jahns J, Madaj-Sterba P, Weisheit S, Kamprad F, Hildebrandt G: Low dose X-irradiation of adjuvant induced arthritis in rats – Efficacy of different fractionation schedules. Strahlenther Onkol. 180:165-172 (2004). PM:14991205

Rödel F, Schaller U, Schultze-Mosgau S, Beuscher HU, Keilholz L, Herrmann M, Voll R, Sauer R, Hildebrandt G: The induction of TGF-ß1 and NF-kB parallels a biphasic time course of leukocyte / endothelial cell adhesion following low-dose X-irradiation. Strahlenther Onkol. 180:194-200 (2004). PM:15057429

Hildebrandt G, Loppnow G, Jahns J, Hindemith M, Anderegg U, Saalbach A, Kamprad F: Inhibition of the iNOS-pathway in inflammatory macrophages by low dose X-irradiation – Is there a time dependence? Strahlenther Onkol. 179:158-166 (2003). PM:12627258

Hildebrandt G, Radlingmayr A, Rosenthal S, Rothe R, Jahns J, Hindemith M, Kamprad F: Low-dose radiotherapy (LD-RT) and the modulation of iNOS-expression in adjuvant arthritis in rats. Int J Radiat Biol. 79:993-1001 (2003). PM:14713577

Österreicher J, Škopek J, Jahns J, Hildebrandt G, Psutka J, Vilasová Z, Tanner JM, Vogt J, Butz T (2003): b1-integrin and IL-1a expression as bystander effect of medium from irradiated cells: the pilot study. Acta Histochem. 105:223-230 (2003). PM:13677615

Rödel F, Kamprad F, Sauer R, Hildebrandt G: Funktionelle und molekulare Aspekte der antiinflammatorischen Wirkung niedrig dosierter Radiotherapie. Strahlenther Onkol. 178:1-9 (2002). PM:11977385

Gershkevitsh E, Hildebrandt G, Wolf U, Kamprad F, Realo E, Trott KR: Chromo-somal aberration in peripheral lymphocytes and doses to the active bone marrow in radiotherapy of prostate cancer. Strahlenther Onkol. 178:36-42 (2002). PM:11977390

Hildebrandt G, Magiorella L, Rödel V, Rödel F, Willis D, Trott KR: Mononuclear cell adhesion and cell adhesion molecule liberation after X-irradiation of activated endothelial cells in vitro. Int J Radiat Biol. 78:315-325 (2002). PM:12020443

Wandel E, Raschke A, Hildebrandt G, Eberle J, Dummer R, Anderegg U, Saalbach A: Fibroblasts enhance the invasive capacity of melanoma cells in vitro. Arch Dermatol Res. 293:601-608 (2002). PM:11875642

Anderegg U, Prieb J, Hildebrandt G, Saalbach A: Minocycline does not alter collagen type I metabolism of dermal fibroblasts in culture. Arch Dermatol Res. 294:103-108 (2002). PM:12029495

Saalbach A, Hildebrandt G, Haustein UF, Anderegg U: The Thy1 / Thy-1-ligand-interaction is involved in binding of melanoma cells to activated Thy-1-positive microvascular endothelial cells. Microvascular Research 64:86-93 (2002). PM:12074634

Rödel F, Kley N, Beuscher HU, Hildebrandt G, Keilholz L, Kern P, Voll R, Herrmann M, Sauer R: Anti-inflammatory effect of low dose X-irradiation and the involvement of a TGF-ß1-induced down-regulation of leucocyte / endothelial cell adhesion. Int J Radiat Biol. 78:711-719 (2002). PM:12194755

Hildebrandt G, Jahns J, Hindemith M, Spranger S, Sack U, Kinne RW, Madaj-Sterba P, Wolf U, Kamprad F: Effects of low dose radiation therapy on adjuvant induced arthritis in rats. Int J Radiat Biol. 76:1143-1153 (2000). PM:10947127

Hildebrandt G, Seed MP, Freemantle CN, Alam CAS, Colville-Nash PR, Trott KR: Mechanisms of the anti-inflammatory activity of low-dose radiation therapy. Int J Radiat Biol. 74:367-378 (1998). PM:9737539

Hildebrandt G, Seed MP, Freemantle CN, Alam CAS, Colville-Nash PR, Trott KR: Effects of low dose ionizing radiation on murine chronic granulomatous tissue. Strahlenther Onkol. 174:580-588 (1998). PM:9830440

Fischer U, Kamprad F, Koch F, Ludewig E, Melzer R, Hildebrandt G: Effekte einer niedrig dosierten Co-60-Bestrahlung auf den Verlauf einer aseptischen Arthritis am Kniegelenk des Kaninchens. Strahlenther Onkol. 174:633-639 (1998). PM:9879351